Cell Culture Media, Supplements, and Reagents
Medchemexpress LLC Azido-peg4-val-cit-pab-oh | 2055024-64-9 | MFCD29918229 | 98.0% | 652.74 g/mol | C29H48N8O9 | 100 MG
Azido-PEG4-Val-Cit-PAB-OH is a cleavable PEG-based linker used for assembling antibody-drug conjugates and other conjugates. It features an azide functional group for click chemistry and a protease-cleavable Val-Cit-PAB spacer that enables enzymatic payload release.
- cleavable PEG-based linker for ADC and conjugate synthesis.
- contains an azide group for CuAAC and SPAAC click reactions.
- protease-sensitive Val-Cit-PAB spacer enabling payload release.
- molecular weight 652.74 g/mol and formula C29H48N8O9.
- high purity (98.0%) with recommended storage conditions for powder and solution.
Medchemexpress LLC ILK-IN-3 25mg | 6975-75-3 | 232.24 g/mol | C10H12N6O | 25 MG
ILK-IN-3 is a small-molecule, orally active inhibitor of integrin-linked kinase (ILK) used in preclinical studies to investigate ILK-mediated signaling and evaluate combination cancer therapies. It has been reported to enhance the anticancer efficacy of docetaxel in orthotopic LCC6 models.
- Orally active small-molecule ILK inhibitor.
- Shown to potentiate docetaxel efficacy in LCC6 orthotopic model.
- High chemical purity (99.62%).
- Molecular formula C10H12N6O; molecular weight ≈ 232.24 g/mol.
- Supplied in research-scale pack sizes, including 25 mg.
- Intended for research use only; not for human therapeutic use.
Medchemexpress LLC PF-06380101 (Aur0101) | 1436391-86-4 | 100.0% | 743.01 g/mol | C39H62N6O6S | 25 MG
PF-06380101 (Aur0101) is an auristatin-class microtubule inhibitor and a cytotoxic dolastatin 10 analogue developed for use as an antibody-drug conjugate (ADC) payload and in oncology research. It shows potent activity in tumor cell proliferation assays and has differential ADME properties compared with other synthetic auristatin analogues. Supplied as a solid for research use only.
- Potent microtubule inhibitor for cancer research.
- Suitable as antibody-drug conjugate (ADC) payload.
- High reported purity for analytical and experimental use.
- White to off-white solid form, easy to handle.
- Recommended storage: powder at -20°C or 4°C; in solvent at -80°C.
- Manufacturer-provided datasheet includes CAS number, formula, and molecular weight.
Medchemexpress LLC Triphenyl compound A | 21306-65-0 | 99.8% | 399.53 g/mol | C21H21NO3S2 | 5 MG
TPh A (Triphenyl Compound A) is a small-molecule research compound that selectively binds the nuclear protein pirin and disrupts the Bcl3-pirin complex. It is supplied as a powder for laboratory use, with high reported purity and analytical characterization suitable for cellular tool compound applications.
- Potent pirin inhibitor with reported Ki ≈ 0.6 μM.
- Disrupts formation of the Bcl3-pirin complex in biochemical assays.
- High purity (99.81%) suitable for research applications.
- Supplied as a powder for straightforward handling and aliquoting.
- Characterized by formula C21H21NO3S2 and molecular weight 399.53 g/mol.
Medchemexpress LLC 1-(1-(2-(piperidin-1-yl)acetyl)piperidin-4-yl)-5-(1-isopropyl-2-oxo-... | 2768712-71-4 | 99.9% | 461.60 g/mol | C27H35N5O2 | 5 MG
CDK9-IN-13 is a research-grade small-molecule inhibitor selective for cyclin-dependent kinase 9 (CDK9). It exhibits potent biochemical inhibition of CDK9 (IC50 <3 nM), displays short half-lives in rodents, and is supplied at high purity for biochemical and cellular studies.
- Potent CDK9 inhibition (IC50 <3 nM)
- Selective kinase profile with reduced off-target activity
- High purity (99.94%) suitable for research assays
- Molecular weight 461.60 g/mol; formula C27H35N5O2
- Available in small mg quantities for screening and validation
Medchemexpress LLC FNC-TP | 2457357-99-0 | 99.9% | 526.16 g/mol | C9H14FN6O13P3 | 5 MG
FNC-TP is the intracellular triphosphate (active) form of a nucleoside reverse transcriptase inhibitor supplied for research applications. It is intended for use in biochemical and cellular assays to study antiviral activity and enzyme interactions, with storage recommendations to preserve stability.
- Active triphosphate form of a nucleoside reverse transcriptase inhibitor.
- Antiviral activity against HIV, HBV, and HCV.
- High purity (>99.9%) suitable for sensitive assays.
- Available in small-mass vials for biochemical and cellular experiments.
- Store frozen and protected from light to maintain stability.
Medchemexpress LLC (1R,2S)-VU0155041 | 1093757-42-6 | 99.1% | 316.18 g/mol | C14H15Cl2NO3 | 5 MG
VU0155041 is a research-grade small molecule that functions as a potent, selective positive allosteric modulator (PAM) of metabotropic glutamate receptor 4 (mGluR4). It has reported sub-micromolar activity and is supplied as a high-purity solid suitable for in vitro pharmacology and preclinical studies.
- Potent, selective positive allosteric modulator of mGluR4 (EC50 ≈ 798 nM human, 693 nM rat).
- High purity: 99.1%.
- Molecular weight: 316.18 g/mol.
- Soluble in DMSO at 100 mg/mL.
- Supplied as a 5 mg solid for laboratory use.
- Applicable to preclinical research, including Parkinson's disease models.
Medchemexpress LLC Mi-389 | 2222635-92-7 | 99.3% | 654.69 g/mol | C35H35FN6O6 | 5 MG
MI-389 is a proteolysis-targeting chimera (PROTAC) that degrades the translation termination factor GSPT1 through recruitment of the CRL4CRBN E3 ligase. It is provided as a research-grade small molecule with reported antiproliferative activity in leukemia cell lines and is intended for in vitro and cellular studies.
Medchemexpress LLC Rad51-in-1 | 2101739-18-6 | 99.9% | 50 MG
RAD51-IN-1 is a small-molecule inhibitor of the RAD51 recombinase, derived from B02, intended for preclinical cancer research to inhibit homologous recombination and reduce RAD51 foci formation in tumor cells.
- Inhibits RAD51-mediated homologous recombination.
- Displays cytotoxic activity in multiple human cancer cell lines with low micromolar IC50 values.
- Reported high purity (99.89%) and solid, yellow to orange physical form.
- Stable as a powder under recommended storage (powder: -20°C for years).
- Available in small solid quantities and as a 10 mM solution in DMSO for in vitro use.
Medchemexpress LLC RBP4 Human HEK293 100ug
Recombinant human Retinol Binding Protein 4 (RBP4) produced in HEK293 cells with a C-terminal human Fc tag, supplied for research use in biochemical and cell-based assays. Available in common research-scale quantities including a 100 μg format, the protein is purified to high purity and supplied with storage guidance to preserve activity.
- Expressed in HEK293 cells for human-like post-translational modifications.
- C-terminal human Fc tag facilitates detection and purification.
- Available in small research-scale quantities, including 100 μg.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Molecular weight approximately 53 kDa.
- Recommended storage at -20°C or -80°C; aliquot to avoid freeze-thaw.